Using biotechnology to enhance host resistance to aflatoxin contamination of corn
نویسندگان
چکیده
Host resistance is the most widely explored strategy for eliminating aflatoxin contamination by Aspergillus flavus. Breeding strategies for developing resistant corn germplasm have been enhanced by the development of new screening tools for field inoculation and for laboratory screening. RFLP analysis of corn populations has highlighted the possibility that different resistance traits can be successfully pyramided into agronomically useful germplasm, while proteomics has impacted the identification of proteins associated with resistance (RAPs). The identification of RAPs has also been enhanced by the discovery of near-isogenic corn lines in progeny generated in a West African breeding program. The characterization of genes of the aflatoxin biosynthetic pathway has provided a foundation for a genomics investigation aimed at understanding the biochemical function and genetic regulation of aflatoxin biosynthesis. Successful inhibition of aflatoxin elaboration may require not only the action of antifungal compounds, but of compounds that block biosynthesis of toxins as well.
منابع مشابه
Toward elucidation of genetic and functional genetic mechanisms in corn host resistance to Aspergillus flavus infection and aflatoxin contamination
Aflatoxins are carcinogenic mycotoxins produced by some species in the Aspergillus genus, such as A. flavus and A. parasiticus. Contamination of aflatoxins in corn profusely happens at pre-harvest stage when heat and drought field conditions favor A. flavus colonization. Commercial corn hybrids are generally susceptible to A. flavus infection. An ideal strategy for preventing aflatoxin contamin...
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